Hi, Thomaston!
Over at the Mandolin Café, there are a few topics on the subject, including information on using a specialized alloy string to tune the highest string/course to B4 at a 25.5" scale length. Here's a couple of them.
https://www.mandolincafe.com/forum/threads/50620-Converting-6-string-to-full-fifth-tuning-my-experimenthttps://www.mandolincafe.com/forum/threads/52587-12-String-Conversion-to-Mandophone-Mandocello-Plus!One easy way to see if it makes sense is to retune a guitar to CGDDAE low to high, which can be done with the strings already on there.
You can use those online fretboard diagram builders to create a chord dictionary for full fifths across six strings/courses. There are a couple which are easier and which span all six strings/courses.
I've had discussions with several curious Fripp acolytes who noticed I was using full fifths instead of crippled fifths, wherein they tried to explain why the minor third at the top was philosophically preferable to a fifth. However none of them actually leveraged that string in usage. I eventually concluded they were desperately trying to justify that last interval as the result of deep thought, instead of just being the compromise required by the technology of the day when it originated.... *laugh*